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Search Results for " cat s "

Targets Recommended: Cysteine Protease

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T16089	MK-0674	Cysteine Protease	Proteases/Proteasome
	MK-0674 是一种可口服且具有选择性和高效性的 cathepsin K 抑制剂（IC50：0.4 nM），抑制 Cat B、Cat F、Cat L 和 Cat S，可用于和代谢相关的疾病。
TQ0116	LY 3000328 Cathepsin S inhibitor	Cysteine Protease	Proteases/Proteasome
	LY 3000328 (Cathepsin S inhibitor) 是 Cathepsin S 的选择性抑制剂，抑制人和小鼠Cat S 的IC50分别为7.7，1.67 nM。
T62494	Cathepsin C-IN-5
	CathepsinC-IN-5 (compound SF38) 为一高效、选择性、口服活性的组织蛋白酶 C (Cat C) 抑制剂，其针对Cat C、Cat L、Cat S、Cat B、Cat K 的IC50s 分别为 59.9 nM、4.26 µM、>5 µM、>5 µM、>5 µM。该化合物能够抑制骨髓和血液中的Cat C活性，降低中性粒细胞丝氨酸蛋白酶（NSP）的激活，并展现抗炎活性。
T68806	Azelnidipine, (S)-
	Azelnidipine, (S)-, is an L-type calcium channel blocker (CCB). Studies have shown that in patients with hypertension (HT) and heart failure preserved ejection fraction (HFpEF), azelnidipine improved the severity of HF and cardiac sympathetic nerve activity compared with cilnidipine, an N-type CCB (Cat#326734).
T37467	SGC 6870N
	Negative control for SGC 6870 (Cat. No. 7182). SGC 6870N is the (S)-enantiomer, which is inactive on PRMT6.
T37931	15(S)-Latanoprost
	15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 μg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys. 15(S)-Latanoprost is a potential impurity in most commercial preparations of the ...
T37401	15(S)-HpEDE
	15(S)-HpEDE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosadienoic acid. Although the biological activities of 15(S)-HpEDE have not been well characterized, it is expected to behave similarly to 15(S)-HpETE (Cat. No. 44720).

化合物

MK-0674

Cat.No: T16089

Synonym:

Target: Cysteine Protease

LY 3000328

Cat.No: TQ0116

Synonym: Cathepsin S inhibitor

Target: Cysteine Protease

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02751	Cathepsin S Protein, Mouse, Recombinant (His) cathepsin S,Cat S	Mouse	HEK293 Cells
	Cathepsin S Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is AAB94925.1.